A work friend of mine was shot through the thigh with a hollow point .45 a few years ago. A negligent discharge by somebody else with a 5" 1911. He got lucky that his femoral artery and the femur itself weren't hit. He now has a scar from the entry and exit as well as a scar where an incision was made to go in and fix some tissue damage. I can post some pics later of his leg that I ha e saved somewhere when I can find them. The recount is what is interesting. He felt no impact from the bullet, felt no pain, did not even know he was shot for a few moments as he tried to figure out where the bullet went. Then he realized his leg was bleeding and sat down and started trying to control the bleed. It still didn't cause him any pain until a few minutes after he realized he was shot. He was conscious all the way to the hospital. It goes to show that when people say handguns are all underpowered, they are correct. Unless you can disrupt the central nervous system and force an adversary to stop, the bullets you're slinging don't matter.